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Literature
Are you ordering SPEP alone to rule out monoclonal gammopathies?

You could be missing 1 out of 8 patients with Multiple Myeloma1,2 . SPEP + FLC + IFE provides >99% diagnostic sensitivity in detection of Multiple Myeloma.¹⁻³
Publication
Guidelines for Laboratory detection and Initial Diagnosis of Monoclonal Gammopathies

Guidelines from the College of American Pathologists in collaboration with the American Association for Clinical Chemistry and the American Society for Clinical Pathology
Publication
Recommendations for Laboratory detection and Initial Diagnosis of Monoclonal Gammopathies

Statements and strengths of recommendations from the College of American Pathologists
Literature
Diagnosis Algorithm

Algorithm for Laboratory detection and Initial Diagnosis of Monoclonal Gammopathies from the College of American Pathologists